Escherichia coli tryptophan operon directs the in vivo synthesis of a leader peptide
Open Access
- 28 February 1986
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 165 (3), 1046-1048
- https://doi.org/10.1128/jb.165.3.1046-1048.1986
Abstract
Here we report the identification of the Escherichia coli trp leader peptide synthesized in vivo. We identified the peptide in UV-irradiated maxicells by selective labeling with radioactive amino acids which are included in the predicted sequence of this peptide. Our results support the hypothesis that translation of the peptide-coding region of the leader RNA has a role in the mechanism of attenuation of biosynthetic operons in general and in the E. coli trp operon in particular.This publication has 28 references indexed in Scilit:
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