A comparison with the axonal reaction
- 1 April 1966
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 16 (4), 398
- https://doi.org/10.1212/wnl.16.4.398
Abstract
Several oxidative enzymes were demonstrated by histochemical methods in spinal motor neurons of patients with Werdnig-Hoffmann disease and of control cases matched for age. Motor neurons of patients with Werdnig-Hoffmann disease showed no evidence of deficiency of any of the enzymes studied. Chromatolytic nerve cells in patients with Werdnig-Hoffmann disease showed an increase in activity of several enzymes. This increase was most striking with the TPNH diaphorase reaction. The histochemical changes in chromatolytic cells in patients with Werdnig-Hoffmann disease resembled the changes observed following axon section in experimental animals.This publication has 5 references indexed in Scilit:
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