Peripheral lymphocyte depletion in gold sodium thiomalate—treated rheumatoid arthritis patients
- 30 June 1988
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 31 (7), 909-913
- https://doi.org/10.1002/art.1780310713
Abstract
It has been reported that gold sodium thiomalate treatment of rheumatoid arthritis reduces the number of peripheral blood lymphocytes. In a prospective, double‐blind, randomized trial comparing gold sodium thiomalate, auranofin, and placebo in the treatment of rheumatoid arthritis, we investigated absolute lymphocyte counts. We found that peripheral lymphocyte counts decreased, but there was no correlation with clinical change in disease activity.This publication has 14 references indexed in Scilit:
- Reduction of peripheral blood lymphocytes in patients receiving gold therapy for rheumatoid arthritis.Annals Of The Rheumatic Diseases, 1985
- Analysis of T cell subsets in the peripheral blood and synovial fluid of patients with rheumatoid arthritis by means of monoclonal antibodies.Annals Of The Rheumatic Diseases, 1983
- Treatment of Intractable Rheumatoid Arthritis with Total Lymphoid IrradiationNew England Journal of Medicine, 1981
- Lymphapheresis in rheumatoid arthritisArthritis & Rheumatism, 1981
- Characterisation of activated lymphocytes in the peripheral blood of patients with rheumatoid arthritis.Annals Of The Rheumatic Diseases, 1981
- Lymphocyte Involvement in Rheumatoid ArthritisArthritis & Rheumatism, 1977
- Inhibition by gold of human lymphocyte stimulation. An in vitro study.Annals Of The Rheumatic Diseases, 1977
- Inhibition of antigen- and mitogen-induced human lymphocyte proliferation by gold compounds.Journal of Clinical Investigation, 1977
- The Effect of In Vivo Hydrocortisone on Subpopulations of Human LymphocytesJournal of Clinical Investigation, 1974
- Lymphocyte characteristics in rheumatic patients and the effect of azathioprine therapyArthritis & Rheumatism, 1974