ON THE CONFORMATION OF THE DISULPHIDE GROUP IN L‐CYSTINE AND ITS DERIVATIVES*

Abstract
The terminal groups in cystine are asymmetric and hence the disulphide group with right and left chirality may not have equal energy. An attempt is made to resolve this problem through energy calculation using semi-empirical methods involving non-bonded and electrostatic interactions and simple Pauling type torsional potential for the disulphide group. The results are discussed in the light of experimental data.

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