HEMORRHAGIC HYPOTENSION IN HEPATECTOMIZED AND BILATERALLY NEPHRECTOMIZED HEPATECTOMIZED DOGS

Abstract

Animals deprived of livers or livers and kidneys can be subjected to prolonged hemorrhagic hypotension and still retain the ability to re-establish and maintain for some time normal arterial pressure following intra-arterial reinfusion of shed blood. This ability is not impaired by exchange transfusion of hepatectomized animals with blood from animals in hemorrhagic hypotension both intact and nephrectomized. Thus, these direct expts. do not demonstrate a critical function of the liver or kidneys in the vascular response to a standardized hemorrhagic hypotension.