Solution-Phase Parallel Synthesis of 115 Homosilatecan Analogues
- 24 June 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Combinatorial Chemistry
- Vol. 5 (5), 617-624
- https://doi.org/10.1021/cc030018g
Abstract
No abstract availableThis publication has 20 references indexed in Scilit:
- Solution-Phase Preparation of a 560-Compound Library of Individual Pure Mappicine Analogues by Fluorous Mixture SynthesisJournal of the American Chemical Society, 2002
- Asymmetric total synthesis of (20R)-homocamptothecin, substituted homocamptothecins and homosilatecansTetrahedron, 2002
- Fluorous Mixture Synthesis: A Fluorous-Tagging Strategy for the Synthesis and Separation of Mixtures of Organic CompoundsScience, 2001
- Novel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood StabilitiesJournal of Medicinal Chemistry, 1999
- Preparation of Highly Functionalized Pyridylmagnesium Reagents for the Synthesis of Polyfunctional PyridinesSynlett, 1998
- Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin AnaloguesJournal of Medicinal Chemistry, 1998
- 7-Silylcamptothecins (silatecans): A new family of camptothecin antitumor agentsBioorganic & Medicinal Chemistry Letters, 1997
- BN 80245: An E-ring modified camptothecin with potent antiproliferative and topoisomerase I inhibitory activitiesBioorganic & Medicinal Chemistry Letters, 1997
- Selective N-functionalization of 6-substituted-2-pyridonesTetrahedron Letters, 1995
- Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albuminJournal of Medicinal Chemistry, 1993