UNILATERAL HYPOVENTILATION IN MAN DURING TEMPORARY OCCLUSION OF ONE PULMONARY ARTERY*

Abstract
In patients with chronic lung disease, occlusion of one pulmonary artery did not increase total ventilation or arterial PCO2. By bronchospirometry we demonstrated a shift in ventilation away from the lung with the occluded artery. This shift was due to bronchoconstriction and atelectasis and could be prevented by inhaling 6 percent CO2 in air or oxygen in the lung without pulmonary arterial blood flow.