MOLECULAR BIOLOGY OF DIABETES INSIPIDUS
- 1 February 1995
- journal article
- review article
- Published by Annual Reviews in Annual Review of Medicine
- Vol. 46 (1), 331-343
- https://doi.org/10.1146/annurev.med.46.1.331
Abstract
▪ Abstract The identification, characterization, and mutational analysis of three different genes, namely the prepro-arginine-vasopressin-neurophysin II gene (prepro-AVP-NPII), the arginine-vasopressin receptor 2 gene (AVPR2), and the vasopressin-sensitive water channel gene (aquaporin-2, AQP2), provide the basis for our understanding of three different hereditary forms of diabetes insipidus: autosomal dominant neurogenic diabetes insipidus, X-linked nephrogenic diabetes insipidus, and autosomal recessive nephrogenic diabetes insipidus, respectively. These advances provide diagnostic tools for physicians caring for these patients.Keywords
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