Relation of Kveim-Antigen Reaction to Lymphadenopathy

Abstract

Kveim tests in 37 selected patients with sarcoidosis demonstrated that a reaction could be related to persistent lymphadenopathy and not to duration or activity of illness. Fourteen asymptomatic patients with marked enlargement of the mediastinal and hilar lymph nodes of long duration all reacted strongly. Positive tests occurred in only three of 12 patients having disease of recent onset with minimal adenopathy, and in only one of 11 with active hepatic or cutaneous sarcoidosis and normal chest roentgenograms.