Enrichment of specific suppressor T cells and characterization of their surface markers.
Open Access
- 1 November 1977
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 146 (5), 1450-1454
- https://doi.org/10.1084/jem.146.5.1450
Abstract
A simple method is described which allows antigen-specific suppressor T cells to be enriched by greater than 100-fold. The enriched cells have the following characteristic markers: Ig-, Thy-1+, Ly-1-, Ly-2,3+, and I-J+. More than 30% of this population could be killed directly by an antiserum specific for the I-J subregion gene product in the presence of complement.Keywords
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