Effect of ACTH Administration on Certain Enzyme Systems in Rat Liver.
- 1 January 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 82 (1), 14-16
- https://doi.org/10.3181/00379727-82-20007
Abstract
1.0 mg ACTH was injected into rats for 8-10 days. Liver slices from these animals showed a decreased methylation of nicotinamide and an increased methylation of guanidoacetic acid. The methylation of homocysteine was unaffected. Tyrosine formation from phenylalanine was inhibited as was uric acid formation from xanthine. Urea production was normal. Endogenous ketone body production and the oxidation of octanoate was increased.Keywords
This publication has 9 references indexed in Scilit:
- THE EFFECTS OF ADRENALECTOMY AND CORTISONE TREATMENT ON FATTY ACID OXIDATION BY MOUSE LIVER HOMOGENATESJournal of Biological Chemistry, 1952
- EFFECTS OF CORTISONE AND PURIFIED PITUITARY GROWTH HORMONE ON KETOGENESIS BY SURVIVING LIVER SLICESAnnals of the New York Academy of Sciences, 1951
- CORTICOIDS AND BODY AND ORGAN WEIGHTS, NITROGEN BALANCE, AND ENZYMESJournal of Biological Chemistry, 1951
- Metabolic action of cortisone: d-Amino acid oxidase and apparent creatinine formationArchives of Biochemistry and Biophysics, 1951
- ANTERIOR PITUITARY EXTRACT AND LIVER METABOLISMJournal of Biological Chemistry, 1951
- EFFECT OF HORMONES UPON THE PRODUCTION OF KETONE BODIES BY RAT LIVER SLICESJournal of Biological Chemistry, 1950
- METHIONINE FORMATION BY TRANSMETHYLATION IN VITROJournal of Biological Chemistry, 1947
- THE EXCRETION OF NICOTINIC ACID DERIVATIVES AFTER INGESTION OF TRYPTOPHANE BY MANJournal of Biological Chemistry, 1947
- Studies on the ketogenic activity of the anterior pituitaryBiochemical Journal, 1938