Escherichia coli strains with multiple DNA repair defects are hyperinduced for the SOS response
- 1 August 1990
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 172 (8), 4719-4720
- https://doi.org/10.1128/jb.172.8.4719-4720.1990
Abstract
Escherichia coli strains defective for the repair of apurinic/apyrimidinic sites and for the UvrABC excision repair pathway could be constructed if they also carried a mutation in ung, which encodes uracil glycosylase, or sulA, which encodes an SOS-inducible inhibitor of septation. The resultant strains were sensitive to alkylation damage and hyperinduced for the SOS response, but had unpredictable spontaneous mutation rates.This publication has 14 references indexed in Scilit:
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