A Comparison of Piribedil, Procyclidine and Placebo in the Control of Phenothiazine-induced Parkinsonism
- 1 June 1977
- journal article
- clinical trial
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 130 (6), 581-585
- https://doi.org/10.1192/bjp.130.6.581
Abstract
Summary: A double-blind, cross-over trial of the effectiveness of piribedil, procyclidine and placebo in the control of parkinsonism induced by fluphenazine decanoate was conducted in sixteen cases of chronic schizophrenia. Procyclidine was shown to be more effective and piribedil less effective than the placebo. Piribedil produced a number of unpleasant effects, including headache, vomiting and malaise.Keywords
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