Comparison of the Antibacterial Activities of Sisomicin and Gentamicin Against Gram-Negative Bacteria

Abstract
Sisomicin was found to be more active on a weight basis than gentamicin against Pseudomonas sp., Klebsiella sp., and indole-positive Proteus . Gentamicin was more active than sisomicin against Escherichia coli, Serratia sp., Enterobacter sp., and Proteus mirabilis . Both antibiotics were very active against methicillin-resistant strains of Staphylococcus aureus .