Acrosoxacin in the treatment of uncomplicated gonorrhoea.
Open Access
- 1 August 1983
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 59 (4), 242-244
- https://doi.org/10.1136/sti.59.4.242
Abstract
Acrosoxacin was given as a single 300 mg oral dose to 105 patients with acute gonorrhoea. Of the 100 patients followed completely there was a 93% cure rate and 33% of men developed postgonococcal urethritis (PGU). This compared with a 97% cure and 30% PGU with 2 megaunits penicillin. The in vitro activity of acrosoxacin in Nottingham against strains of Neisseria gonorrhoeae showed that it was a highly active agent with 90% of strains inhibited by a concentration of 0.03 mg/l.This publication has 4 references indexed in Scilit:
- Penicillinase-producing Neisseria gonorrhoeae in Great Britain, 1977-81: alarming increase in incidence and recent development of endemic transmission.BMJ, 1982
- In-vitro antigonococcal activity of rosoxacin (WIN 35213).Sexually Transmitted Infections, 1981
- Cultural diagnosis of gonorrhoea with modified New York City (MNYC) medium.Sexually Transmitted Infections, 1978
- Single-dose treatment of uncomplicated gonorrhoea in males with minocycline.Sexually Transmitted Infections, 1975