Studies on the half life time of rat liver transfer RNA species
- 18 November 1970
- journal article
- Published by Wiley in FEBS Letters
- Vol. 11 (2), 78-80
- https://doi.org/10.1016/0014-5793(70)80496-3
Abstract
The tRNA fraction, extracted from very high speed supernatant fluid, from livers of rats injected with 3H-orotic acid, attained maximum specific activity after a little over 24 hr and, thereafter, decayed with an apparent half life of 5 days. This behaviour of tRNA was indistinguishable from that of liver rRNA and the acid soluble pool. Chromatography of tRNA, doubly labelled during a period of short synthesis and of prolonged decay, on a BD cellulose column, indicated that individual tRNA species turn over at a constant rate with respect to one another.Keywords
This publication has 10 references indexed in Scilit:
- Modifications of ribonucleic acid by chemical carcinogens. II. In vivo reaction of N-2-acetylaminofluorene with rat liver ribonucleic acidBiochemistry, 1970
- Effect of cortisone on rat liver transfer ribonucleic acidBiochemistry, 1969
- Studies on the Synthesis and Degradation of Proteins of the Endoplasmic Reticulum of Rat LiverJournal of Biological Chemistry, 1969
- Distribution of radioactivity between the acid-soluble pool and the pools of RNA in the nuclear, nonsedimentable and ribosome fractions of rat liver after a single injection of labeled orotic acidBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1968
- The Separation of Soluble Ribonucleic Acids on Benzoylated Diethylaminoethylcellulose*Biochemistry, 1967
- Physiology of rat-liver polysomes. The stability of messenger ribonucleic acid and ribosomesBiochemical Journal, 1967
- The turnover of ribosomal RNA and soluble RNA in the rabbit uterusBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
- Turnover of Liver Ribosomes in Fed and in Fasted RatsJournal of Biological Chemistry, 1966
- Studies on the turnover and messenger activity of rat-liver ribonucleic acidsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
- Turnover of Ribosomal RNA in Rat LiverScience, 1965