This article is based on the experience of the last twenty years, during which time more than 5,000 patients addicted to morphinism were treated. None of these patients suffered from an organic disease that necessitated the continuance of the drug. In all instances the narcotic was withdrawn in less than two weeks' time, with no special preparation of the patient before beginning treatment. Withdrawal of the drug was sudden in every case without resorting to scopolamin in doses sufficient to produce delirium. There were no acute withdrawal symptoms, drug psychoses or serious asthenic symptoms. The total number of deaths from all causes in these addicts was six. There were no deaths due to withdrawal of the drug or treatment. These patients were no more trouble than any other patients when they actually knew that nothing they could do or say would produce for them another dose of morphin. EFFECTS OF