The Effects of an Adhesive in the Middle Ear
- 1 December 1980
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 106 (12), 734-736
- https://doi.org/10.1001/archotol.1980.00790360012004
Abstract
• This study investigated the effects of enbucrilate (Histoacryl) on the middle ear. Small amounts of the adhesive were used in 81 middle-ear operations performed on 50 rabbits. Light microscopic investigation of these ears 1, 2, and 3 months after surgery showed bone necrosis and a granulation tissue reaction surrounded by foreign-body giant cells. Inner-ear changes were observed in a third of the cases. Therefore, enbucrilate should only be used with extreme care and in minute quantities and never near the labyrinthine capsule. (Arch Otolaryngol 106:734-736, 1980)This publication has 4 references indexed in Scilit:
- The Histological Effect Of An Adhesive In The Middle EarActa Oto-Laryngologica, 1973
- Experiences with Tissue Adhesives in Middle Ear OperationsORL, 1972
- Human middle ear transplantsThe Journal of Laryngology & Otology, 1971
- A trial of adhesives in reconstructive middle-ear surgeryThe Journal of Laryngology & Otology, 1969