A Practical Method for the Determination of Fibrinogen
- 1 October 1959
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 5 (5), 414-420
- https://doi.org/10.1093/clinchem/5.5.414
Abstract
A practical method for the determination of fibrinogen is presented in which thrombin is used to convert fibrinogen to fibrin and the resultant clot is hydrolyzed. The concentration of protein may be determined by the usual biuret reagent or by the phenol-biuret reagent of Lowry, if small amounts of fibrinogen are to be measured. The mean normal plasma value was found to be 295 ± 17.0 mg./100ml. Albumin or serum may be used instead of fibrinogen as a more convenient protein standard.Keywords
This publication has 6 references indexed in Scilit:
- Turbidimetric Analysis of Fibrinogen and Gamma Globulin with Ammonium Sulfate by Different Photometric TechnicsClinical Chemistry, 1958
- PHOTOMETRIC MICRODETERMINATION OF PLASMA FIBRINOGEN WITH A THROMBIN-NINHYDRIN PROCEDUREJournal of Biological Chemistry, 1954
- DETERMINATION OF CEREBROSPINAL FLUID PROTEIN WITH THE FOLIN PHENOL REAGENT1952
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951
- Preparation and Properties of Serum and Plasma Proteins. XV. Some Factors Influencing the Quantitative Determination of Fibrinogen1,2Journal of the American Chemical Society, 1947
- CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. III. AMINO ACID COMPOSITION OF PLASMA PROTEINS 1JCI Insight, 1944