Detection of brain activation using oxygenation sensitive functional spectroscopy
Open Access
- 1 January 1994
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 31 (1), 85-90
- https://doi.org/10.1002/mrm.1910310115
Abstract
A nonwater-suppressed localized spectroscopy experiment using the PRESS-sequence has been used to study the signal changes of the water resonance during cortical activation. Significant effects with an effect-to-noise ratio up to 50:1 for a single shot experiment have been observed upon photic stimulation. The exceedingly high signal-to-noise ratio of the experiment was used to demonstrate signal changes as low as 0.1% after electrical stimulation of the median nerve.Keywords
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