The Volume Distribution and Equilibrium Time of Para-Aminohippurate
- 1 December 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 72 (3), 616-618
- https://doi.org/10.3181/00379727-72-17517
Abstract
The PAH space in 14 normal subjects, detd. by subtracting that excreted in the urine from that infused intraven. with a constant speed pump, was 35.9 [plus or minus] 7.3% of body wt. If an initial priming dose is omitted and plasma level allowed to rise slowly, it takes 75 min. to reach 90% of eventual plasma concn., 100 min. to reach 95%,, and 150 min. to reach 99% in the avg. subject.Keywords
This publication has 6 references indexed in Scilit:
- THE MEASUREMENT OF GLOMERULAR AND TUBULAR PLASMA FLOW IN THE NORMAL AND DISEASED HUMAN KIDNEY 1JCI Insight, 1949
- OBSERVATIONS ON THE CLEARANCE METHOD OF DETERMINING RENAL PLASMA FLOW WITH DIODRAST, PARAAMINOHIPPURIC ACID (PAH) AND PARA - ACETYLAMINOHIPPURIC ACID (PACA)1949
- COMPARISON OF THE CONSTANT INFUSION AND URINE COLLECTION TECHNIQUES FOR THE MEASUREMENT OF RENAL FUNCTION 1JCI Insight, 1948
- RENAL OXYGEN CONSUMPTION IN MAN DURING ABDOMINAL COMPRESSIONJCI Insight, 1948
- A METHOD OF DETERMINING THE SPECIFIC RENAL FUNCTIONS OF GLOMERULAR FILTRATION, MAXIMAL TUBULAR EXCRETION (OR REABSORPTION), AND EFFECTIVE BLOOD FLOW USING A SINGLE INJECTION OF A SINGLE SUBSTANCE1947
- DETERMINATION OF THE VOLUME OF THE EXTRACELLULAR FLUID OF THE BODY WITH RADIOACTIVE SODIUMThe Journal of Experimental Medicine, 1941