INCREASED ACTIVITY OF RAT-LIVER MESSENGER-RNA AND OF ALBUMIN MESSENGER-RNA MODULATED BY THIOACETAMIDE
- 1 January 1978
- journal article
- research article
- Vol. 38 (7), 2043-2047
Abstract
Administration of thioacetamide to rats increased the activity of liver mRNA in the wheat germ protein synthesis assay. The synthesis of total protein was increased about 2.5-fold after 4 days of treatment. Treatment was associated with an increase in the relative quantity of polyadenylic acid-containing RNA. Immunoprecipitation studies showed that albumin synthesis directed by the mRNA was increased disproportionately, reaching a level 5-6 times the control after 4 days of thioacetamide administration.This publication has 7 references indexed in Scilit:
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