Acid-catalysed methanolysis of methylphenylphosphinic amides: stereochemistry and mechanism

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Abstract
Methylphenylphosphinic amide (1) and its N-phenyl (2) and N-p-nitrophenyl (3) analogues undergo methanolysis with complete inversion of configuration in 0·15 M HCl-MeOH; in 1·5 M HCl–MeOH the extent of inversion decreases in the order (1) > (3) > (2).