Use of the single radial diffusion technique for influenza antibody surveys.
- 1 January 1973
- journal article
- research article
- Vol. 49 (4), 327-32
Abstract
A survey of antibody to the influenza A/Hong Kong/1/68 (H3N2) and the variant A/England/42/72 (H3N2) was carried out by two methods, haemagglutination-inhibition (HI) and single radial diffusion (SRD). A comparison of the sensitivity of the two tests indicated that the proportion of sera that produced a zone of 2.5 mm or larger in the SRD tests was equivalent to the proportion that gave HI titres of 1: 40 or more. The test was carried out on serum samples collected from various regions of England. The results showed that approximately 70% had antibody to the A/HK/1/68 virus and only 35% had antibody to A/England/42/72. The SRD test was shown to have several practical advantages for seroepidemiological studies.This publication has 7 references indexed in Scilit:
- Hong Kong influenza in the Royal Air Force 1968–70Epidemiology and Infection, 1973
- A Quantitative, Single-Radial-Diffusion Test for Immunological Studies with Influenza VirusJournal of General Virology, 1972
- The polypeptide composition of influenza a virusesVirology, 1971
- Serological evidence of infection with A2 Hong Kong influenza virus during the epidemic in Britain 1968-9.1969
- Influenza in Britain 1967–68Epidemiology and Infection, 1969
- Characterization of the Ribonucleoprotein and Neuraminidase of Influenza A Viruses by ImmunodiffusionJournal of General Virology, 1969
- Future influenza vaccines and the use of genetic recombinants.1969