Concordance Study on Population Database Samples Using the PowerPlex™ 16 Kit and AmpFℓSTR® Profiler Plus™ Kit and AmpFℓSTR® COfiler™ Kit
- 1 May 2001
- journal article
- other
- Published by ASTM International in Journal of Forensic Sciences
- Vol. 46 (3), 637-641
- https://doi.org/10.1520/jfs15016j
Abstract
Over 500 population database samples comprising African Americans, Bahamians, and Southwestern Hispanics were typed using the PowerPlex™ 16 and the Profiler Plus™ COfiler™ kits. There was only one sample in which a typing difference was observed. An FGA heterozygote profile was observed using the PowerPlex™ 16 primers, and a single allele FGA profile was observed using Profiler Plus primers. Thus, the extant data suggest that the primers used in the PowerPlex™ 16, Profiler Plus™, and COfiler™ kits are reliable for typing reference samples destined for use in CODIS. In addition, African American, Bahamian, and Southwestern Hispanic databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic. The application of the product rule is valid for estimating the rarity of a multiple loci profile consisting of these two and the 13 core STR loci.Keywords
This publication has 15 references indexed in Scilit:
- Population Data on the Thirteen CODIS Core Short Tandem Repeat Loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and TrinidadiansJournal of Forensic Sciences, 1999
- Italian population data on two new short tandem repeat loci: D2S1338 and Penta EForensic Science International, 1999
- Subtyping of the HLA-DQA1 Locus and Independence Testing with PM and STR/VNTR LociJournal of Forensic Sciences, 1998
- Estimating minimum allele frequencies for DNA profile frequency estimates for PCR-based lociInternational journal of legal medicine, 1996
- Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groupsGenomics, 1992
- Population Genetics of Hypervariable Loci: Analysis of PCR Based VNTR Polymorphism Within a PopulationPublished by Springer Nature ,1991
- Sibling and parent--offspring correlation estimation with variable family size.Proceedings of the National Academy of Sciences, 1981
- SAMPLING VARIANCES OF HETEROZYGOSITY AND GENETIC DISTANCEGenetics, 1974
- The Robustness of Homogeneity Tests in 2 x N TablesBiometrics, 1965
- Standard calculations for evaluating a blood-group systemHeredity, 1951