The experimental production of high-level intraepidermal splits
- 1 January 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 102 (1), 75-83
- https://doi.org/10.1111/j.1365-2133.1980.tb05674.x
Abstract
The effects of trypsin at 37.degree. and 4.degree. C on adhesion between keratinocytes in normal human epidermis were assessed by light microscopy and EM. Evidence for the contribution of extracellular and intracellular factors to keratinocyte adhesion and for changes in the nature of adhesion in the granular layer was found. Trypsinization at 4.degree. C produced a high-level intraepidermal split identical in location and intercellular route to that observed in the staphylococcal scaled skin syndrome.This publication has 15 references indexed in Scilit:
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