Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression
Open Access
- 22 November 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 462 (1-2), 57-60
- https://doi.org/10.1016/s0014-5793(99)01512-4
Abstract
In normal epithelial cells, impaired cell‐matrix contact leads to induction of programmed cell death, a process that has been termed ‘anoikis’. We investigated the role of p53 and other apoptotic pro...Keywords
This publication has 15 references indexed in Scilit:
- Fibronectin Is Required to Prevent Thyroid Cell Apoptosis through an Integrin-Mediated Adhesion MechanismJournal of Clinical Endocrinology & Metabolism, 1998
- Interference of BAD (Bcl-xL/Bcl-2-Associated Death Promoter)-Induced Apoptosis in Mammalian Cells by 14-3-3 Isoforms and P11Molecular Endocrinology, 1997
- Integrins and anoikisCurrent Opinion in Cell Biology, 1997
- FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling ComplexCell, 1996
- Inactivation of Bcl-2 by phosphorylation.Proceedings of the National Academy of Sciences, 1995
- Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell deathCell, 1995
- X-rays strike p53 againNature, 1994
- Anchorage dependence, integrins, and apoptosisCell, 1994
- Disruption of epithelial cell-matrix interactions induces apoptosisThe Journal of cell biology, 1994
- Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesisThe Journal of Pathology, 1984