USE OF THE VENTRAL PROSTATE IN THE ASSAY OF HUMAN CHORIONIC GONADOTROPHIN
- 1 November 1950
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 5 (3), 226-234
- https://doi.org/10.1530/acta.0.0050226
Abstract
Injn. of human chorionic gonadotropin (HCG) increases the wt. of the ventral prostate of Sprague-Dawley rats, hypophysectomized at 22 days of age and injected from the 3d- 7th days post-hypophysectomy with 1.0 ml. of the test soln subcut./day. The wt. increase is directly proportional to the dose from 0.5 to at least 2 I.U. of HCG. The assay is not affected by the presence of follicle stimulating hormone, which does increase the wt. of seminal vesicles The smallest amt. of HCG detectable was 0.6 ug. protein N of a crystalline prepn. ("Gonadex", Leo) or 0 5 units of international standard, using 5 animals for assay.Keywords
This publication has 4 references indexed in Scilit:
- TESTICULAR DEFICIENCY: A CLINICAL AND PATHOLOGIC STUDY*†Journal of Clinical Endocrinology & Metabolism, 1950
- CRYSTALLINE HUMAN CHORIONIC GONADOTROPHIN AND ITS BIOLOGICAL ACTIONActa Endocrinologica, 1948
- Experience with a Quantitative Test for Normal or Decreased Amounts of Follicle Stimulating Hormone in the Urine in Endocrinological DiagnosisJournal of Clinical Endocrinology & Metabolism, 1943
- INTERSTITIAL CELL STIMULATING HORMONE I. BIOLOGICAL PROPERTIES11Endocrinology, 1940