Experimental Lens-Induced Granulomatous Endophthalmitis in Common Laboratory Animals
- 1 January 1982
- journal article
- research article
- Published by S. Karger AG in Ophthalmic Research
- Vol. 14 (4), 292-297
- https://doi.org/10.1159/000265205
Abstract
Guinea pigs and mice after immunization with lens proteins were observed to develop a typical form of experimental phacoanaphylactic endophthalmitis after lens injury. Sensitization to lens protein elicited a good antibody response in rabbits, however no disease developed after lens injury. This is another example of frequent discrepancies between autoimmune responses and autoimmune disease and indicates the importance of investigating mechanisms of phlogogenicity in autoimmune disease.Keywords
This publication has 7 references indexed in Scilit:
- Macrophage triggering by aggregated immunoglobulins. I. Delayed effect of IgG aggregates or immune complexes.The Journal of Immunology, 1981
- DISSOCIATION BETWEEN HUMORAL AND CELLULAR IMMUNE-RESPONSES TO LENS ANTIGENS1981
- Experimental Allergic UveitisArchives of Ophthalmology (1950), 1979
- Lung Injury Produced by Immune Complexes of Varying CompositionThe Journal of Immunology, 1978
- Immunopathology of the lens. II. Humoral and cellular immune responses to homologous lens antigens and their roles in ocular inflammation.British Journal of Ophthalmology, 1977
- Immunopathology of the lens. I. Humoral and cellular immune responses to heterologous lens antigens and their roles in ocular inflammation.British Journal of Ophthalmology, 1977
- Lens-induced uveitisExperimental Eye Research, 1962