Activity of Phospholipase A2 in the Inner Membrane of Rat-Liver Mitochondria
- 1 October 1981
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 119 (3), 517-521
- https://doi.org/10.1111/j.1432-1033.1981.tb05638.x
Abstract
The inner membrane of rat liver mitochondria contains a highly active phospholipase A2 which has alkaline pH optimum and requires Ca2+ in the micromolar range. The phospholipase is particularly active on the endogenous phosphatidylethanolamine and releases relatively high amounts of docosahexanoic acid. The phospholipase A2 of mitochondria or mitoplasts is not dependent on calmodulin. Using fluorescamine-labeled mitoplasts there are indications that the enzyme is localized on both sides of the inner membrane.This publication has 29 references indexed in Scilit:
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