Two new stable polybrominated salicylanilides for antibacterial use in soap and detergent products

Abstract

The versatility of two brominated salicylanilides as antiseptic agents and germicides in soap and detergent products for use on skin, hair, hard sur‐faces and in fabrics is discussed. Both preparations show stability at elevated temp and pressure and compatibility with many surfactant vehicles. They are free of primary irritation and sensitization, including sunlight‐induced irritation. A mixture of di‐ and tribromosalicylanilide is currently being used in toilet bars, shampoos, laundry products, disinfectant sprays and multi‐purpose disinfectant products. The substantivity to fabrics is further characterized by stability to heat and hydrolysis by alkalinity. Essentially pure 3,4艂,5 tribromosalicylanilide is resistant to discoloration, making it particularly suitable for use in white and pastel colored toilet bars. It has excellent substantivity to skin and provides long‐lasting action against odor‐causing and pathogenic bacteria.