Alkaline phosphatase of the calf intestine hydrolyzes phospholipids
- 22 April 1985
- journal article
- Published by Wiley in FEBS Letters
- Vol. 183 (2), 417-422
- https://doi.org/10.1016/0014-5793(85)80822-x
Abstract
Pure alkaline phosphatase of the calf intestine is able to hydrolyze phosphatidylinositol 4,5-diphosphate (TPI) to phosphatidylinositol and Pi and to dephosphorylate phosphatidic acid. This phosphomonoesterase activity shows a considerably high specifie activity when an incubation medium at neutral pH containing 3 mM deoxycholate is used. The activity is inhibited by low concentrations of Ca2+. The enzyme has no detectable phosphodiesterase activity under the conditions tested.Keywords
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