A chicken leukocyte common antigen: biochemical characterization and ontogenetic study
- 1 January 1987
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 17 (2), 287-290
- https://doi.org/10.1002/eji.1830170221
Abstract
A monoclonal antibody, designated CL-1, was produced by immunizing mice with chicken peripheral blood lymphocytes (PBL) and selected in an indirect immuno-fluorescence assay. CL-1 characterizes a cell surface antigen expressed on all chicken hemopoietic cells except mature erythrocytes. Cells stained by CL-1 were detected at early stages of embryonic development in the various hemopoietic compartments. CL-1 reacts with two chicken PBL proteins of 200 kDa and 215 kDa which are probably the homologues of the T-200 and B-220 antigens previously described in the mouse. Moreover, CL-1 does not react with quail hemopoietic tissues and can be useful in experiments using quail-chick chimeras to study the ontogeny of the hemopoietic system.This publication has 20 references indexed in Scilit:
- Tissue distribution and ontogenic appearance of a chicken T lymphocyte differentiation markerEuropean Journal of Immunology, 1985
- Detection of avian hematopoietic cell surface antigens with monoclonal antibodies to myeloid cellsExperimental Cell Research, 1983
- Preferential but Nonexclusive Expression of Macromolecular Antigens on B‐Lineage CellsImmunological Reviews, 1983
- Diffuse intraembryonic hemopoiesis in normal and chimeric avian developmentDevelopmental Biology, 1981
- Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule.The Journal of Experimental Medicine, 1981
- Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiationCell, 1979
- The predominant heavily glycosylated glycoproteins at the surface of rat lymphoid cells are differentiation antigensEuropean Journal of Immunology, 1978
- Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200.The Journal of Experimental Medicine, 1978
- Tracing of cells of the avian thymus through embryonic life in interspecific chimeras.The Journal of Experimental Medicine, 1975
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970