Amantadine Monotherapy of Chronic Hepatitis C Patients Infected with Genotype 1b
- 1 January 2000
- journal article
- Published by Taylor & Francis in Scandinavian Journal of Infectious Diseases
- Vol. 32 (5), 575-576
- https://doi.org/10.1080/003655400458965
Abstract
We aimed to test the efficacy of amantadine in chronic hepatitis C (CHC) patients infected with genotype b. Twenty patients completed treatment with amantadine HCl, 100 mg b.i.d., for 6 months. Non-sustained biochemical improvement was observed without loss of HCV-RNA. We conclude that amantadine monotherapy is not effective in CHC.Keywords
This publication has 5 references indexed in Scilit:
- Long-term efficacy of interferon-alpha and ursodeoxycholic acid in treatment of chronic type C hepatitis.Digestive Diseases and Sciences, 1997
- Treatment of Chronic Hepatitis C with AmantadineDigestive Diseases and Sciences, 1997
- A second-generation method of genotyping hepatitis C virus by the polymerase chain reaction with sense and antisense primers deduced from the core geneJournal of Virological Methods, 1996
- Prophylaxis and Treatment of InfluenzaNew England Journal of Medicine, 1990
- Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis†Hepatology, 1981