RÔLE OF CARBON DIOXIDE AND OF THE HINDBRAIN IN AGENE-INDUCED CANINE EPILEPSY

Abstract

Inhalation of 20% CO2 and 80% O2 is synergistic with the toxicity induced by the ingestion of flour treated with nitrogen trichloride. It accentuates existing electroencephalographic abnormalities and can precipitate a seizure in a susceptible animal. These are seen first in leads over the hindbrain and characteristically when the inhalation starts or shortly after it is terminated.