Liquid Chromatographic Separation of the Enantiomers of Chiral Secondary Alcohols as Their α-Naphthyl Urethane Derivatives
- 1 July 1988
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 11 (9-10), 2165-2173
- https://doi.org/10.1080/01483918808069047
Abstract
The enantiomers of α-naphthyl urethane derivatives of a wide variety of chiral secondary alcohols are separable by liquid chromatography on a chiral stationary phase derived from a conformationally restricted β-amino acid. In many instances separation factors are sufficiently great (1.5–6.5) to enable preparative separations to be effected.Keywords
This publication has 2 references indexed in Scilit:
- Broad spectrum resolution of optical isomers using chiral high-performance liquid chromatographic bonded phasesJournal of Chromatography A, 1980
- Design of chiral derivatizing agents for the chromatographic resolution of optical isomers. Asymmetric synthesis of some chiral fluoroalkylated aminesThe Journal of Organic Chemistry, 1977