The Clinical Pharmacokinetics of Levofloxacin
- 1 February 1997
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 32 (2), 101-119
- https://doi.org/10.2165/00003088-199732020-00002
Abstract
Levofloxacin is a fluoroquinolone antibiotic and is the optical S-(−) isomer of the racemic drug substance ofloxacin. It has a broad spectrum of in vitroactivity against Gram-positive and...Keywords
This publication has 38 references indexed in Scilit:
- Rapid stereospecific high-performance liquid chromatographic determination of levofloxacin in human plasma and urineJournal of Pharmaceutical and Biomedical Analysis, 1997
- Open-label crossover study to determine pharmacokinetics and penetration of two dose regimens of levofloxacin into inflammatory fluidAntimicrobial Agents and Chemotherapy, 1995
- Accumulation of a newly developed fluoroquinolone, OPC-17116, by human polymorphonuclear leukocytesAntimicrobial Agents and Chemotherapy, 1993
- Pharmacodynamics of intravenous ciprofloxacin in seriously ill patientsAntimicrobial Agents and Chemotherapy, 1993
- [Chemotherapy of biliary tract infections (XXXVII). Excretion into bile and gallbladder tissue levels of levofloxacin and its clinical effect in biliary tract infections].1992
- [Laboratory and clinical studies on levofloxacin].1992
- Comparative penetration of lomefloxacin and other quinolones into human phagocytesAmerican Journal Of Medicine, 1992
- Enantioselective disposition of ofloxacin in humansAntimicrobial Agents and Chemotherapy, 1991
- Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity.Cell Structure and Function, 1990
- Pharmacokinetics of three newer quinolones in pregnant and lactating womenAmerican Journal Of Medicine, 1989