Synthesis and Antiviral Evaluation of Analogs of Adenosine-N1-Oxide and 1-(Benzyloxy)Adenosine
- 1 August 1998
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 17 (8), 1409-1443
- https://doi.org/10.1080/07328319808003478
Abstract
The activity of a series of compounds related to adenosine-N 1-oxide (1) and 1-(benzyloxy)adenosine (42) against vaccinia virus has been determined both in vitro and in a vaccinia mouse tailpox model. Significant activities have been found both in vitro and in vivo for a number of the synthetic compounds.Keywords
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