Partial deletions and trisomies of chromosome 13; Mapping of bands associated with particular malformations

Abstract
New techniques of human karyotyping accurately define the banding pattern of 6 new cases with partial duplication or deficiency of chromosome 13. It now seems possible to draw a rough map of chromosome 13, correlating observed malformations and phenotypic features with specific chromosome regions. Partial monosomy shows clinical features which are the antithesis of the corresponding trisomic phenotype.