Chronic ingestion of Mn3O4by young rats: Tissue accumulation, distribution, and depletion
- 1 February 1981
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 7 (2), 263-272
- https://doi.org/10.1080/15287398109529977
Abstract
Mn accumulation, distribution, and disappearance were evaluated in selected tissues of preweanling rats dosed daily with particulate Mn 3 O 4 for 12 or 27 d postpartum. Significant findings include a high rate of Mn absorption and localization in tissues, especially the cerebrum, hypothalamus, and pituitary. In these tissues, the return of Mn concentrations to control levels was much slower when Mn dosing was continued beyond 18–20 d postpartum.This publication has 18 references indexed in Scilit:
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