Theoretical simulation of ionic transport through a transmembrane channel
- 31 July 1983
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Cell Biology
- Vol. 61 (8), 856-859
- https://doi.org/10.1139/o83-109
Abstract
The two-site model of Urry for the ionic conduction through a gramicidin A channel has been confirmed by theoretical calculations, using a method developed at this laboratory, which yields the potential energy profile of the ion along the channel. Preliminary results show that the pore closure could start with the spatial rearrangement of the —HN—CH3 terminal chain under the influence of the ion already in the channel.This publication has 3 references indexed in Scilit:
- Theoretical prediction of protein antigenic determinants from amino acid sequencesCanadian Journal of Chemistry, 1982
- Conformation of gramicidin A channel in phospholipid vesicles: a 13C and 19F nuclear magnetic resonance study.Proceedings of the National Academy of Sciences, 1979
- The dimeric nature of the gramicidin A transmembrane channel: Conductance and fluorescence energy transfer studies of hybrid channelsJournal of Molecular Biology, 1977