γ-Glutamyl Transpeptidase in Brain Capillaries: Possible Site of a Blood-Brain Barrier for Amino Acids
- 5 April 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 184 (4132), 66-68
- https://doi.org/10.1126/science.184.4132.66
Abstract
A fraction containing capillaries and rich in γ-glutamyl transpeptidase was isolated from homogenates of bovine brain cortex by density gradient centrifugation. The enzyme was localized in the endothelial cells by a histochemical procedure. γ-Glutantyl transpeptidase may function in the transfer of some amino acids across the blood-brain barrier.Keywords
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