STUDIES ON THE STORAGE OF THE OESTROGEN-PRECURSOR IN THE INTERSTITIAL GLAND OF THE OVARY OF RATS TREATED WITH OESTRADIOL BENZOATE AND PROGESTERONE
- 1 January 1949
- journal article
- research article
- Published by S. Karger AG in Cells Tissues Organs
- Vol. 8 (1-2), 91-95
- https://doi.org/10.1159/000140400
Abstract
Estradiol benzoate and progesterone (20 and 5 mg. per day, respectively, or every 2d day) produce a storage of the estrogen-precursor in the interstitial gland of rat ovaries in intact but not in hypophysectomized rats. These steroids, therefore do not cause a storage by a direct action on the interstitial cells but act via the hypophysis. The ovary is subjected to a certain basal gonadotrophic stimulus so that the balance between precursor storage and its transformation becomes positive.Keywords
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