Evidence for the Role of a Siderophore in Promoting Vibrio anguillarum Infections
- 1 October 1986
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 132 (10), 2949-2952
- https://doi.org/10.1099/00221287-132-10-2949
Abstract
Vibrio anguillarum strain 775 harbouring the virulence plasmid pJM1 produces a plasmid-mediated siderophore that can crossfeed siderophore-deficient, receptor-proficient mutants of V. anguillarum in vitro. Experimental infections of salmonid fishes with mixtures consisting of the wild-type strain and a siderophore-deficient, receptor-proficient mutant resulted in recovery of both the wild-type and the mutant strain, while in infections with mixtures consisting of the wild-type strain and a siderophore-deficient, receptor-deficient mutant only the wild-type strain could be recovered. These results suggest that the V. anguillarum plasmid-mediated siderophore is produced in vivo in a diffusible form and that it is an important factor of virulence.This publication has 7 references indexed in Scilit:
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