Effects of an Antibody to a Highly Purified Na + , K + -ATPase from Canine Renal Medulla: Separation of the “Holoenzyme Antibody” into Catalytic and Cardiac Glycoside Receptor-Specific Components
- 1 June 1974
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 71 (6), 2449-2452
- https://doi.org/10.1073/pnas.71.6.2449
Abstract
An antiserum was prepared against a highly purified Na(+), K(+)-adenosine triphosphatase (ATP phosphohydrolase, EC 3.6.1.3). Purification and fractionation yielded two globulin components, one of which appears specific for a digitalis glycoside receptor site or binding conformation and the other for a catalytic site or conformation.Keywords
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