Precise and combinatorial PEGylation generates a low-immunogenic and stable form of human growth hormone
- 1 March 2017
- journal article
- research article
- Published by Elsevier in Journal of Controlled Release
- Vol. 249, 84-93
- https://doi.org/10.1016/j.jconrel.2017.01.029
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81530090, 81673342, 21572015)
- National Key Research and Development Program of China (2016YFA0501500)
This publication has 43 references indexed in Scilit:
- The Conformation of the Poly(ethylene glycol) Chain in Mono-PEGylated Lysozyme and Mono-PEGylated Human Growth HormoneBioconjugate Chemistry, 2011
- RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sitesNature Chemical Biology, 2011
- Strain‐Promoted Alkyne–Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate BiosynthesisChemBioChem, 2011
- Optimized clinical performance of growth hormone with an expanded genetic codeProceedings of the National Academy of Sciences, 2011
- Sortase-catalyzed transformations that improve the properties of cytokinesProceedings of the National Academy of Sciences, 2011
- Codon reassignment in the Escherichia coli genetic codeNucleic Acids Research, 2010
- An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coliJournal of Molecular Biology, 2009
- A Long-Acting, Mono-PEGylated Human Growth Hormone Analog Is a Potent Stimulator of Weight Gain and Bone Growth in Hypophysectomized RatsEndocrinology, 2007
- Site-specific PEGylation of proteins containing unnatural amino acidsBioorganic & Medicinal Chemistry Letters, 2004
- Comparison of a Structural and a Functional EpitopeJournal of Molecular Biology, 1993