PREVENTION OF ADRENAL-REGENERATION HYPERTENSION BY AN ALDOSTERONE-BLOCKER
- 1 February 1959
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 64 (2), 299-300
- https://doi.org/10.1210/endo-64-2-299
Abstract
Chronic treatment of rats with the aldosterone-blocker 3-(3-oxo-17[beta]-hydroxy-4-androsten-17[alpha]-yl) propionic acid gamma-lactone prevented adrenal-regeneration hypertension and the accompanying cardiac hypertrophy. Unaffected were: mortality, body weight, saline intake, renal and adrenal hypertrophy.Keywords
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