Holomycin and an antibiotic(MM 19290) related to tunicamycin, metabolites of Streptomyces clavuligerus.
- 1 January 1979
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 32 (6), 549-554
- https://doi.org/10.7164/antibiotics.32.549
Abstract
S. clavuligerus produces penicillin N, several cephalosporins and the .beta.-lactamase inhibitor clavulanic acid. The detection, isolation and properties of further metabolites of this culture, MM 21801 and MM 19290, are described. MM 21801 was identified as the antibiotic holomycin. MM 19290 was shown to be related to tunicamycin, an antibiotic complex obtained from cultures of S. lysosuperificus.This publication has 4 references indexed in Scilit:
- The Structure of TunicamycinAgricultural and Biological Chemistry, 1977
- Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerusAntimicrobial Agents and Chemotherapy, 1977
- Holomycin and N-propionylholothin, antibiotics produced by a cephamycin C producer.The Journal of Antibiotics, 1977
- Stoffwechselprodukte von Actinomyceten 17. MitteilungHolomycinHelvetica Chimica Acta, 1959