COMMUNICATION: FAILURE OF MENOPAUSAL URINE CONCENTRATES TO INDUCE EGG EXTRUSION IN FEMALE XENOPUS FROG TEST FOR PREGNANCY*

Abstract
Urine concentrates of 86 [female][female] who had missed one or more menstrual periods and who were passing through the early phases of the climacteric were tested on Xenopus frogs. No egg-extrusion response was found in the case of any patient tested. The use of the S. African clawed frog (Xenopus laevis) in differentiating pregnancy from early menopause is suggested.