Characterization of benzoxaborole-based antifungal resistance mutations demonstrates that editing depends on electrostatic stabilization of the leucyl-tRNA synthetase editing cap
Open Access
- 16 August 2011
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 585 (19), 2986-2991
- https://doi.org/10.1016/j.febslet.2011.08.010
Abstract
► Isolation of a novel LeuRS resistance mutation to benzoxaborole anti‐fungal drugs. ► Resistance site is located in the hinge of a cap structure that closes over the editing active site. ► A salt br...Keywords
Funding Information
- National Institutes of Health (GM063789)
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